MEDICATION ADHERENCE AND ACCESS TO HEALTH SERVICES IN RELATION TO MDR-TB CASES

Abstract

Background: The spread of antibiotic resistance genes is an ecological and public health issue, one of which is tuberculosis. Mycobacterium tuberculosis is intrinsically resistant to many antibiotics, restricting the number of compounds available for treatment. The aim of this study was to analyze the medication adherence and access to health services influencing the incidence of MDR-TB in pulmonary public hospital, Bogor, Indonesia. Methods: This study used descriptive analytic correlative method with cross sectional approach. The sample in this study were patients with MDR-TB as evidenced by the results of the rapid test examination who were on medication for less than 24 months obtained by purposive sampling technique totaling 140 respondents. Bivariate analysis using the chi-square test with a significance value> 0.05. Results: The result of bivariate test obtained a p-value of 0.018 or p0.05 was obtained, which means that there is no relationship between acces to health services and the occurrence of MDR. Conclusions: As conclusion, adherence is factor were related to the MDR-TB case, while access to health to health services has no correlation to MDR-TB case. In addition to the adherence variable which is an internal factor affecting medication, other external factors that can affect the incidence of antibiotic resistance in tuberculosis patients need to be investigated.